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KMID : 0356620100250010078
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Journal of Korean Society of Endocrinology
2010 Volume.25 No. 1 p.78 ~ p.83
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A Case of Complete Agenesis of the Dorsal Pancreas in a Patient with Newly Diagnosed Diabetes Mellitus
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Kim Dong-Pil
Park Kang-Seo
Kim Dong-Sun
Ko Bong-Suk
Lee Je-Hae
Lee Jae-Hyuk
Shin Jong-Ho
Kim Byung-Joon
Kim Hyun-Jin
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Abstract
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Agenesis of the dorsal pancreas is a rare congenital anomaly caused by underdevelopment or agenesis of the dorsal pancreatic bud that forms the upper head, neck, body and tail of the pancreas. We report a case of agenesis of the dorsal pancreas, which was found under examination of diabetes mellitus (DM). A 16-year-old girl was transferred to our hospital because of a positive urine glucose reading during a school-conducted examination. Abdominal computed tomography and magnetic resonance cholangiopancreatography revealed the deficit of the pancreatic body and tail. Diabetes-associated autoimmune antibodies were negative in a blood test. Decreased β-cell function was demonstrated by oral glucose tolerance and glucagon stimulation tests. Although the notion that agenesis of the dorsal pancreas leads to decreased endocrine or exocrine function is controversial, the results of this study suggest that we should consider these causes of diabetes mellitus. When treating a young patient with diabetes mellitus, we should consider causes of diabetes mellitus such as congenital anomaly or maturity onset diabetes, in addition to type 1 and type 2 diabetes mellitus.
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KEYWORD
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Agenesis of dorsal pancreas, Diabetes mellitus, Insulin
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